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Sports and exercise are important and contribute to maintaining a healthy defense of the body. Due to very intensive training and severe physical or mental stress, professional athletes become more often infected (predominantly influenza infections, urinary tract infections and diarrhea) because the immune system weakens with high efforts. Laboratory medical examinations show that the immune parameters in the blood initially grow under load, after which they fall below the initial level. The consequences can be loss of performance to long-term athletic failure.